
Tesofensine
Tesofensine has randomized human trials showing weight loss, having started as a candidate for neurodegenerative disease. It is a triple monoamine...
About:
A triple monoamine reuptake inhibitor, not a peptide, tested in phase II obesity trials with reported weight loss.
What does this peptide do?
Backed by human trial data, narrower than the strongest evidence. Research focuses on obesity and weight loss.

Obesity research
Tested in phase II obesity trials.

Weight loss
Those trials reported weight loss as an outcome.
Evidence grade
BHighest evidence grade among the graded claims: B. Grades reflect study strength, not benefit.
What are the benefits and side effects of this peptide
What research says it may help with
- Tesofensine has randomized human trials showing weight loss, having started as a candidate for neurodegenerative disease.
Who should avoid it
- People who are pregnant or breastfeeding
- Children and adolescents
- People taking antidepressants or stimulants, given the monoamine mechanism
- Known hypersensitivity to the compound
- Uncontrolled high blood pressure
See the safety section. Absence of a flag is not evidence of safety.
A grade reflects evidence strength, not a recommendation to use this compound; a strong grade can attach to a harmful effect.

How to store this peptide
Lyophilized storage
Store at room temperature, below 25 °C, in a dry place.
Storage Handling
Keep the container tightly closed and away from moisture.
Related research
Related research is coming soon for this peptide.


