Dual GIP/GLP-1 receptor agonist studied for weight management and glucose control.

GLP-1 receptor agonist researched for appetite regulation and metabolic health.

Triple-receptor agonist explored for next-generation weight management research.

AICAR is one of the most used laboratory activators of AMPK, and that identity is well documented in a systematic review. Disease model evidence,...

SS-31 is unusual here: its clinical form, elamipretide, has been through randomized controlled trials. In primary mitochondrial myopathy, the...

5-Amino-1MQ is a small molecule NNMT inhibitor, not a peptide, although it is sold alongside peptides. The verified evidence is preclinical:...

Tesofensine has randomized human trials showing weight loss, having started as a candidate for neurodegenerative disease. It is a triple monoamine...

Liraglutide is a licensed medicine with substantial randomized evidence: dedicated obesity trials at the higher dose, and pooled analyses showing...

Dulaglutide is a licensed weekly medicine with randomized evidence for glycaemic control and, through pooled class analyses, reduced...

Cagrilintide has randomized human trials, both alone and combined with semaglutide, showing meaningful weight loss in people with overweight or...

Exenatide was the first licensed GLP-1 receptor agonist, developed from exendin-4 found in Gila monster venom. Randomized comparative trials show...

Survodutide has randomized phase 2 evidence in both obesity and metabolic dysfunction associated steatohepatitis, with dose-dependent effects on...

Mazdutide has randomized trials spanning early phase through later studies, conducted largely in Chinese populations, showing weight loss and...

Adipotide is a prohibitin-targeting peptidomimetic that produced weight loss in animal studies, including primates. It never progressed to human...

Setmelanotide is a licensed medicine for rare genetic obesity syndromes, with pooled trial evidence and guideline coverage in Bardet-Biedl...

The verified literature for this fragment is thin and old: a 1978 animal study of C-terminal growth hormone fragments that reported effects on...