AICAR
AICAR is one of the most used laboratory activators of AMPK, and that identity is well documented in a systematic review. Disease model evidence,...
About:
An AMP-activated protein kinase activator studied as an exercise mimetic in animals, with limited human infusion studies.
What does this peptide do?
Human evidence is limited or indirect. Research focuses on AMPK activation and exercise mimetic.
AMPK activation
One of the most used laboratory activators of AMPK.
Exercise mimetic research
Studied as an exercise mimetic in animals.
Evidence grade
CHighest evidence grade among the graded claims: C. Grades reflect study strength, not benefit.
What are the benefits and side effects of this peptide
What research says it may help with
- AICAR is one of the most used laboratory activators of AMPK, and that identity is well documented in a systematic review.
- Disease model evidence, such as fatty liver improvement, comes from mice.
- Human administration as acadesine is described in review literature.
Who should avoid it
- People who are pregnant or breastfeeding
- Children and adolescents
- Athletes subject to anti-doping rules, as AICAR is prohibited in sport
- Known hypersensitivity to the compound
See the safety section. Absence of a flag is not evidence of safety.
A grade reflects evidence strength, not a recommendation to use this compound; a strong grade can attach to a harmful effect.
How to store this peptide
Typically sold as a lyophilized powder. Reconstituted solutions are perishable, need refrigeration, and require clean handling to avoid contamination.
Lyophilized storage
Store at −20 °C, protected from light.
Reconstituted storage
Keep at 2–8 °C and use within a short period. For longer storage, aliquot and freeze at −20 °C.
Storage Handling
Avoid repeated freeze–thaw cycles. Let the vial reach room temperature before opening.
Related research
Related research is coming soon for this peptide.
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