Every figure here is computed from MaxHuman’s own evidence reviews. For each citation we record whether the study was run in people or in animals, and what kind of study it was. Nothing is estimated. Last updated 2026-08-19.
The headline numbers
329 citations verified against primary literature
194 distinct studies
36 published evidence reviews
92% of studies included human data
20% are randomised controlled trials
1 of 10 graded compounds have no human trial behind them at all
Human trial evidence, by compound
Graded on the controlled human evidence we could verify, worst first. The grade ignores whether findings were positive: a compound whose trials all failed still scores well, because the question was answered.
C · BPC-157 — Human data, but no controlled trials. 21 studies checked, no human trials, 71% of the evidence base in people.
B · GHK-Cu — Some human trial evidence. 29 studies checked, 2 human trials, 83% of the evidence base in people.
B · TB-500 — Some human trial evidence. 10 studies checked, 1 human trial, 90% of the evidence base in people.
B · IGF-1 LR3 — Some human trial evidence. 10 studies checked, 1 human trial, 100% of the evidence base in people.
B · MOTS-c — Some human trial evidence. 8 studies checked, 1 human trial, 88% of the evidence base in people.
B · Selank — Some human trial evidence. 6 studies checked, 2 human trials, 83% of the evidence base in people.
A · Semaglutide — Strong human evidence. 14 studies checked, 4 human trials, 100% of the evidence base in people.
A · Sermorelin — Strong human evidence. 10 studies checked, 5 human trials, 100% of the evidence base in people.
A · Tesamorelin — Strong human evidence. 8 studies checked, 7 human trials, 100% of the evidence base in people.
A · CJC-1295 — Strong human evidence. 5 studies checked, 3 human trials, 100% of the evidence base in people.
How the grades work
A — three or more randomised controlled trials in people
B — at least one randomised controlled trial in people
C — people were studied, but nothing was controlled
D — animal and laboratory evidence only
F — no studies found
Method
Each review extracts the factual claims an article makes, searches PubMed and Europe PMC for studies that could support them, and verifies whether each study actually does. Studies that fail verification are not cited. Population and study design are recorded for every citation that survives, and this page aggregates those records. Compounds with fewer than three verified studies are excluded, because a grade on one paper would overstate what we know.
Any figure on this page may be quoted with attribution to MaxHuman.
