
Argireline
Argireline has more evidence behind it than most cosmetic peptides: controlled studies measuring wrinkle endpoints, a pilot clinical study, and...
About:
A cosmetic hexapeptide derived from SNAP-25, marketed for wrinkle reduction.
What does this peptide do?
Supported by randomised human trials. Research focuses on wrinkle reduction.

Wrinkle reduction
A cosmetic hexapeptide marketed for wrinkle reduction.
Evidence grade
AHighest evidence grade among the graded claims: A. Grades reflect study strength, not benefit.
What are the benefits and side effects of this peptide
What research says it may help with
- Argireline has more evidence behind it than most cosmetic peptides: controlled studies measuring wrinkle endpoints, a pilot clinical study, and inclusion in a systematic review of topical peptides for skin ageing.
Who should avoid it
- People who are pregnant or breastfeeding
- Children and adolescents
- Known hypersensitivity to cosmetic peptide ingredients
See the safety section. Absence of a flag is not evidence of safety.
A grade reflects evidence strength, not a recommendation to use this compound; a strong grade can attach to a harmful effect.

How to store this peptide
Lyophilized storage
Store per the product labelling, away from heat and direct light.
Storage Handling
Keep the container closed; do not decant into unsterile packaging.
Related research
Related research is coming soon for this peptide.


