
DSIP
DSIP was isolated from work on sleep transmission in rabbits in the 1970s, and that origin is well documented. Its sleep effects rest on old...
About:
A nonapeptide first isolated from rabbit brain in the 1970s and tested in small human sleep studies with mixed results.
What does this peptide do?
Human evidence is limited or indirect. Research focuses on sleep.

Sleep research
Tested in small human sleep studies with mixed results.
Evidence grade
CHighest evidence grade among the graded claims: C. Grades reflect study strength, not benefit.
What are the benefits and side effects of this peptide
What research says it may help with
- Its sleep effects rest on old reviews describing animal findings and early reports, with no controlled human trial verified here.
- A modern evidence base for sleep benefits in people is absent.
Who should avoid it
- People who are pregnant or breastfeeding
- Children and adolescents
- People taking sedatives or sleep medication, where no interaction data has been published
- Known hypersensitivity to peptide preparations
See the safety section. Absence of a flag is not evidence of safety.
A grade reflects evidence strength, not a recommendation to use this compound; a strong grade can attach to a harmful effect.

How to store this peptide
Typically sold as a lyophilized powder. Reconstituted solutions are perishable, need refrigeration, and require clean handling to avoid contamination.
Lyophilized storage
Store at −20 °C, protected from light.
Reconstituted storage
Keep at 2–8 °C and use within a short period. For longer storage, aliquot and freeze at −20 °C.
Storage Handling
Avoid repeated freeze–thaw cycles. Let the vial reach room temperature before opening.


