DSIP

A nonapeptide first isolated from rabbit brain in the 1970s and tested in small human sleep studies with mixed results.

What research shows

DSIP was isolated from work on sleep transmission in rabbits in the 1970s, and that origin is well documented. Its sleep effects rest on old reviews describing animal findings and early reports, with no controlled human trial verified here. A modern evidence base for sleep benefits in people is absent.

Evidence strength

Highest evidence grade among the graded claims: C. Grades reflect study strength, not benefit.

Safety context

See the safety section. Absence of a flag is not evidence of safety.

No endorsement

A grade reflects evidence strength, not a recommendation to use this compound; a strong grade can attach to a harmful effect.