Semax
Human data comes from Russian stroke research: one clinical study followed 110 patients after ischemic stroke, without a randomized controlled...
About:
A synthetic analogue of the ACTH(4-10) fragment with proposed neurotrophic effects, developed and studied mainly in Russia.
What does this peptide do?
Human evidence is limited or indirect. Research focuses on neurotrophic effects and stroke.
Neurotrophic effects
Proposed neurotrophic effects, studied mainly in Russia.
Stroke research
One clinical study followed patients after ischaemic stroke.
Evidence grade
CHighest evidence grade among the graded claims: C. Grades reflect study strength, not benefit.
What are the benefits and side effects of this peptide
What research says it may help with
- Human data comes from Russian stroke research: one clinical study followed 110 patients after ischemic stroke, without a randomized controlled design in what we verified.
- Mechanism evidence, including BDNF induction, is from rat studies.
- No human trials of attention or memory effects were verified, and long-term safety data has not been published.
Who should avoid it
- People who are pregnant or breastfeeding
- Children and adolescents
- People taking prescription neurological or psychiatric medication, where no interaction data has been published
- Known hypersensitivity to peptide preparations
See the safety section. Absence of a flag is not evidence of safety.
A grade reflects evidence strength, not a recommendation to use this compound; a strong grade can attach to a harmful effect.
How to store this peptide
Typically sold as a nasal solution or a lyophilized powder. Opened or reconstituted solutions are perishable, need refrigeration, and require clean handling to avoid contamination.
Lyophilized storage
Store at −20 °C, protected from light.
Reconstituted storage
Keep at 2–8 °C and use within a short period. For longer storage, aliquot and freeze at −20 °C.
Storage Handling
Avoid repeated freeze–thaw cycles. Let the vial reach room temperature before opening.
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