LL-37

The only human cathelicidin antimicrobial peptide, studied extensively for antimicrobial and wound-healing activity.

What research shows

LL-37 is unusual in this library for having randomized human trials, all in chronic wound care, where closure measures were the endpoint. Its antimicrobial activity is documented across laboratory work, and cathelicidin levels track vitamin D status in pooled human data.

Evidence strength

Highest evidence grade among the graded claims: B. Grades reflect study strength, not benefit.

Safety context

See the safety section. Absence of a flag is not evidence of safety.

No endorsement

A grade reflects evidence strength, not a recommendation to use this compound; a strong grade can attach to a harmful effect.